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Next Generation Sequencing (NGS)

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Next-Generation Sequencing (NGS):- It is also known as high-throughput sequencing, is a revolutionary technology that has transformed the field of genomics. It enables scientists to rapidly and cost-effectively sequence large amounts of DNA or RNA, providing valuable insights into the genetic makeup of various organisms. NGS has had a profound impact on various disciplines, including biomedical research, personalized medicine, agriculture, and environmental studies. Let's delve into its history, origin, introduction, method of working, benefits, harms, major discoveries using it, and some of the challenges associated with NGS. History and Origin :- The origins of sequencing can be traced back to the 1970s when Frederick Sanger developed the first DNA sequencing method (known as Sanger sequencing). This method involved the chain-termination technique and was the gold standard for many years, but it was labor-intensive, time-consuming, and expensive. The term "next-g...